The Detroit Lions’ 2025 opponents will be a challenging mix of divisional foes and cross-conference rivals. The Lions will face each of their NFC North division rivals twice, as well as playing one game each against teams from the AFC North, AFC South, NFC East, and NFC West.
The Lions’ most difficult games in 2025 will likely come against the Green Bay Packers and Minnesota Vikings, who are both perennial contenders in the NFC North. The Lions will also have to contend with the Baltimore Ravens and Kansas City Chiefs, two of the top teams in the AFC. However, the Lions will also have some favorable matchups in 2025, including games against the Jacksonville Jaguars and Houston Texans, two of the worst teams in the NFL in recent years.